Does the fasting-mimicking diet really switch on autophagy in people, or only in mice? A new pilot randomized trial in 30 healthy adults tested ProLon and a second FMD formulation against control. By the end of the roughly 6-day diet, the groups differed in autophagic flux, weight, glucose, ketones, and insulin resistance. But those differences did not hold at every time point, and the trial was small and sponsored by ProLon's maker. Here is the protocol, what it showed, and who should think twice.
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